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Enhance.MD Review (2026): Pricing, Medications & Is It Legit?

DSBy David Smith, Editor Last verified Sep 5, 2026
Enhance.MD logo
Our rating
8.4 / 10
Lowest verified all-in semaglutide price after month one that includes metabolic labs. Tiered Core/Advanced/Elite plans reward longer commitments.
Best for: You want labs included and can commit to a 12-month plan
Starting price
$112/mo
first month Core semaglutide, then $212/mo on 12-month plan
Membership fee: None
Check if you qualify → Compare all programs
Quick answer

Enhance.MD is a US telehealth program prescribing compounded GLP-1 medication through licensed clinicians. Pricing starts at $112/mo (first month Core semaglutide, then $212/mo on 12-month plan). Lowest verified all-in semaglutide price after month one that includes metabolic labs. Tiered Core/Advanced/Elite plans reward longer commitments.

At a glance

Starting price$112/mo · first month Core semaglutide, then $212/mo on 12-month plan
Membership feeNone
MedicationsCompounded semaglutide (GLP-1 Core); Compounded tirzepatide (Advanced); Semaglutide + tirzepatide (Elite); Microdose tirzepatide; NAD+ therapy / wafers
FormsWeekly injection, Injection / sublingual
InsuranceNo (HSA/FSA eligible)
States servedNot published
Consult feeIncluded; optional free consultation booking
Consultation typeAsync intake + optional consultation
Labs requiredYes; metabolic labs every 6 months, included
ShippingFree
Cancellation100% refund if found ineligible during onboarding
Pharmacy partner503A compounding pharmacies (not named)
Founded / HQNot published · Lewes, Delaware

Pricing breakdown

Enhance.MD includes medication in the prices below. Most "starting" prices are first-month or prepay promotions; compare on the recurring rate. Verified 5 September 2026 against brand-owned pages where available.

PlanCore semaglutide 12-mo
MedicationCompounded semaglutide
Price$212/mo
Billing12-month (billed every 48 wks) · First month $112; same price all doses
PlanCore semaglutide 6-mo
MedicationCompounded semaglutide
Price$224/mo
Billing6-month
PlanCore semaglutide 3-mo
MedicationCompounded semaglutide
Price$237/mo
Billing3-month
PlanCore semaglutide monthly
MedicationCompounded semaglutide
Price$249/mo
BillingMonthly
PlanAdvanced tirzepatide 12-mo
MedicationCompounded tirzepatide
Price$280/mo
Billing12-month · First month $180
PlanAdvanced tirzepatide 6-mo
MedicationCompounded tirzepatide
Price$296/mo
Billing6-month
PlanAdvanced tirzepatide 3-mo
MedicationCompounded tirzepatide
Price$313/mo
Billing3-month
PlanAdvanced tirzepatide monthly
MedicationCompounded tirzepatide
Price$329/mo
BillingMonthly
PlanElite (sema + tirz)
MedicationCompounded semaglutide + tirzepatide
Price$322/mo
BillingMonthly · First month $222
Hidden costs check
  • Consult fee: Included; optional free consultation booking
  • Shipping: Free
  • Membership: None
  • Labs: Yes; metabolic labs every 6 months, included
  • Cancellation: 100% refund if found ineligible during onboarding
Cheapest recurring alternatives we track
  1. LevelsRx$150/mo
  2. Joi + Blokes$199/mo
  3. TrimRx$199/mo

Medications offered

Compounded
semaglutide (GLP-1 Core)
Weekly injection · Starting dose: Not published
Compounded
tirzepatide (Advanced)
Weekly injection · Starting dose: Not published
Compounded
Semaglutide + tirzepatide (Elite)
Weekly injection · Starting dose: Not published
Compounded
Microdose tirzepatide
Weekly injection · Starting dose: 1 mg/wk
Compounded
NAD+ therapy / wafers
Injection / sublingual · Starting dose: Not published

Compounded GLP-1 medications are not FDA-approved products. A licensed clinician decides whether any medication is appropriate.

How Enhance.MD works

1
IntakeAsync intake
2
ID checkPhoto ID and selfie
3
Clinician reviewPhysicians of Enhance Wellness PC & iThriveMD PC
4
PaymentMedication included in plan price
5
DeliveryFree

Who it's for

A good fit if
  • You want labs included and can commit to a 12-month plan
  • $212/mo semaglutide with labs every 6 months included
  • Same price all doses; tirzepatide from $280/mo
Look elsewhere if
  • Best prices require a 12-month commitment
  • States served not published
  • You need a program that bills insurance directly

Pros and cons

Pros
  • +$212/mo semaglutide with labs every 6 months included
  • +Same price all doses; tirzepatide from $280/mo
  • +LegitScript-approved; refund if ineligible
Cons
  • Best prices require a 12-month commitment
  • States served not published
  • Shipping timing not published

Enhance.MD vs. alternatives

Enhance.MDLevelsRxJoi + Blokes
Recurring price$212/mo$150/mo$199/mo
Medication includedYesYesYes
Membership feeNoneNoneNone separate
MedicationsSema, TirzSema, TirzSema, Tirz
Clinician responseAsync intake + optional consultationAsync intake + clinician reviewAsync intake + coaching consult
InsuranceNoYesNo
Our rating8.4 / 108.0 / 108.2 / 10

Is Enhance.MD legit?

Prescribers: Physicians of Enhance Wellness PC & iThriveMD PCPharmacy: 503A compounding pharmaciesLegitScript approvedHQ: Lewes, Delaware

Enhance.MD operates as a telehealth platform. Prescribers: Physicians of Enhance Wellness PC & iThriveMD PC; Medical Director Dr. Erik Stark. Pharmacy: 503A compounding pharmacies (not named). Headquarters: Lewes, Delaware. LegitScript: Approved. Trustpilot: Not published. BBB: Not published. Notes: Offer IDs 3253 and 3137 both resolve to this company; distinct from enhanced.com (Enhanced Group Inc.). Compounded GLP-1s are not FDA-approved products; the FDA declared the semaglutide shortage resolved on 21 Feb 2025 and on 30 Apr 2026 proposed removing semaglutide, tirzepatide and liraglutide from the 503B bulks list, so compounded availability can change at any time.

Enhance.MD FAQ

Is Enhance.MD legit?
Enhance.MD uses physicians of enhance wellness pc & ithrivemd pc and 503a compounding pharmacies (not named). LegitScript status: Approved. Offer IDs 3253 and 3137 both resolve to this company; distinct from enhanced.com (Enhanced Group Inc.).
How much does Enhance.MD cost per month?
From $112/mo (first month Core semaglutide, then $212/mo on 12-month plan). Medication is included. Membership: None.
Does Enhance.MD accept insurance?
No (HSA/FSA eligible)
Which medications does Enhance.MD prescribe?
Compounded semaglutide (GLP-1 Core); Compounded tirzepatide (Advanced); Semaglutide + tirzepatide (Elite); Microdose tirzepatide; NAD+ therapy / wafers.
Does it require labs?
Yes; metabolic labs every 6 months, included
Which states does Enhance.MD serve?
Not published. Not served: Not published.
Can I cancel Enhance.MD?
100% refund if found ineligible during onboarding
Are the medications FDA-approved?
Compounded semaglutide and tirzepatide are not FDA-approved products and their availability can change if the FDA finalises its proposed 503B bulks-list exclusion.

Bottom line

Lowest verified all-in semaglutide price after month one that includes metabolic labs. Tiered Core/Advanced/Elite plans reward longer commitments. Best if you want labs included and can commit to a 12-month plan.

Check if you qualify → Not sure you qualify? Take the quiz
Sources
  1. Enhance.MD Advanced tirzepatide page — accessed Sep 5, 2026
  2. Enhance.MD homepage (Core pricing) — accessed Sep 5, 2026
  3. FDA: Human drug compounding — accessed Sep 1, 2026

DoIQualify may earn a referral fee if you enrol through links on this page. This does not affect our rating. We are not a healthcare provider; eligibility and prescribing decisions are made by each program's licensed clinicians. Prices verified Sep 5, 2026 and may change. How we rank · Medical disclaimer

Enhance.MD · $112/mo
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