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Enhance.MD Review 2026: Monthly Fee vs Real All-In Cost

DSBy David Smith, Editor Last verified Sep 20, 2026 About DoIQualify
Enhance.MD logo
Our rating
8.4 / 10
Publishes every plan price, includes metabolic labs every six months and keeps the price the same at every dose. The $212 headline needs a 12-month plan billed every 48 weeks; paying as you go is $249, and billing runs every 28 days.
Best for: You want labs included and can commit to a 12-month plan
Starting price
$112/mo
first month Core semaglutide; then $212 per 4 weeks on the 12-month plan, $249 on the 1-month plan
Membership fee: None
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Quick answer

Enhance.MD charges $249 every 4 weeks for compounded semaglutide on its 1-month plan, falling to $212 on a 12-month plan that is billed every 48 weeks, with medication included, as of Sep 20, 2026. Its price includes metabolic labs, provider visits, medication and shipping. Billing runs on a 28-day cycle, which means 13 charges a year, not 12.

What to watch for

A “month” is 28 days, and the $212 price is a 48-week prepay. Enhance.MD’s FAQ says membership renews automatically every 28 days, so a year contains 13 billing cycles. On the 1-month plan that is 13 charges of $249, about $3,237 a year by our arithmetic. The advertised $212 applies only to the 12-month plan, which its product page says is “Billed every 48 weeks”. We found no published refund terms for the prepaid 3, 6 or 12-month plans; its terms say only that “full subscription and payment terms are provided at checkout”.

Source: Enhance.MD FAQ: How can I renew my membership?

Thirteen billing cycles a year.

Enhance.MD’s FAQ states its cycle plainly: renewal every 28 days. Programs that bill by calendar month charge 12 times a year, so multiply Enhance.MD’s four-week price by 13, not 12, when you compare a year’s cost.

Source: Enhance.MD FAQ

Enhance.MD in short

Starting price$112/mo · first month Core semaglutide, then $212/mo on 12-month plan
Membership feeNone
MedicationsCompounded semaglutide (GLP-1 Core); Compounded tirzepatide (Advanced); Semaglutide + tirzepatide (Elite); Microdose tirzepatide; NAD+ therapy / wafers
FormsWeekly injection, Injection / sublingual
InsuranceNo (HSA/FSA eligible)
States servedNot published
Consult feeIncluded; optional free consultation booking
Consultation typeAsync intake + optional consultation
Labs requiredYes; metabolic labs every 6 months, included
ShippingFree
CancellationPause or cancel any time by email or phone; renews every 28 days; refund if found ineligible
Pharmacy partnerTru Meds Rx, Strive Pharmacy, Pharmacy Hub (per its FAQ)
Founded / HQNot published · Lewes, Delaware
What we couldn’t verify
  • States served: Not published
  • Founded / HQ: Not published · Lewes, Delaware
As of Sep 20, 2026, Enhance.MD did not publish these details on the pages we checked. Ask the program before you pay. We do not fill gaps with guesses.

Enhance.MD costs explained

Prices below were read from Enhance.MD’s own product pages on Sep 20, 2026. Its FAQ says they include lab work, provider visits, medication and shipping. Each “month” is a 4-week cycle.

PlanCore semaglutide 12-mo
MedicationCompounded semaglutide
Price$212/mo
Billing12-month (billed every 48 wks) · First month $112; same price all doses
PlanCore semaglutide 6-mo
MedicationCompounded semaglutide
Price$224/mo
Billing6-month
PlanCore semaglutide 3-mo
MedicationCompounded semaglutide
Price$237/mo
Billing3-month
PlanCore semaglutide monthly
MedicationCompounded semaglutide
Price$249/mo
BillingMonthly
PlanAdvanced tirzepatide 12-mo
MedicationCompounded tirzepatide
Price$280/mo
Billing12-month · First month $180
PlanAdvanced tirzepatide 6-mo
MedicationCompounded tirzepatide
Price$296/mo
Billing6-month
PlanAdvanced tirzepatide 3-mo
MedicationCompounded tirzepatide
Price$313/mo
Billing3-month
PlanAdvanced tirzepatide monthly
MedicationCompounded tirzepatide
Price$329/mo
BillingMonthly
PlanElite (sema + tirz)
MedicationCompounded semaglutide + tirzepatide
Price$322/mo
BillingMonthly · First month $222
Hidden costs check
  • ✓Consult fee: Included; optional free consultation booking
  • ✓Shipping: Free
  • ✓Membership: None
  • ✓Labs: Yes; metabolic labs every 6 months, included
  • ✓Cancellation: 100% refund if found ineligible during onboarding
Lower-priced recurring alternatives we track
  1. Strut Health — $129/mo
  2. LevelsRx — $150/mo
  3. HealthRX — $165/mo

Before you pay: what a GLP-1 headline price leaves out · cancelling, renewals and refunds

Estimate your all-in monthly cost with our savings calculator.

Treatments Enhance.MD offers

Compounded
semaglutide (GLP-1 Core)
Weekly injection · Starting dose: Not published
Compounded
tirzepatide (Advanced)
Weekly injection · Starting dose: Not published
Compounded
Semaglutide + tirzepatide (Elite)
Weekly injection · Starting dose: Not published
Compounded
Microdose tirzepatide
Weekly injection · Starting dose: 1 mg/wk
Compounded
NAD+ therapy / wafers
Injection / sublingual · Starting dose: Not published

Compounded GLP-1 medications are not FDA-approved products. A licensed clinician decides whether any medication is appropriate.

The Enhance.MD sign-up process

1
IntakeAsync intake
2
ID checkPhoto ID and selfie
3
Clinician reviewPhysicians of Enhance Wellness PC & iThriveMD PC
4
PaymentMedication included in plan price
5
DeliveryFree

Is Enhance.MD the right choice for you?

A good fit if
  • ✓You want labs included and can commit to a 12-month plan
  • ✓$212/mo semaglutide with labs every 6 months included
  • ✓Same price all doses; tirzepatide from $280/mo
Look elsewhere if
  • ✕You want to pay month to month at the headline price
  • ✕You need refund terms in writing before prepaying
  • ✕You need a program that bills insurance directly

These points are about the program, not about you. For the medical side, see the general GLP-1 eligibility criteria. A licensed clinician makes every prescribing decision.

Enhance.MD: benefits and trade-offs

Pros
  • +Every plan price is published before intake
  • +Metabolic labs every 6 months included, per its product pages
  • +Same price at every dose; refund if found ineligible, per its FAQ
Cons
  • −$212 needs a 12-month plan billed every 48 weeks; pay-as-you-go is $249
  • −Bills every 28 days: 13 cycles a year
  • −No published refund terms for prepaid plans

Enhance.MD alongside comparable programs

Enhance.MDLevelsRxJoi + Blokes
Recurring price$249/mo$150/mo$179/mo
Medication includedYesYesYes
Membership feeNoneNoneNone separate
MedicationsSema, TirzSema, TirzSema, Tirz
Clinician responseAsync intake + optional consultationAsync intake + clinician reviewAsync intake + coaching consult
InsuranceNoYesNo
Our rating8.4 / 108.0 / 106.2 / 10

Is Enhance.MD a legitimate provider?

Prescribers: Physicians of Enhance Wellness PC & iThriveMD PCPharmacies: Tru Meds Rx, Strive Pharmacy, Pharmacy HubLegitScript not checkedHQ: Lewes, Delaware

Enhance.MD names its partner pharmacies in its FAQ: Tru Meds Rx, Strive Pharmacy and Pharmacy Hub. It publishes a support email and phone line. We found no FDA warning letter to Enhance.MD on Sep 20, 2026, and its Trustpilot score is 4.0 from 160 reviews with 14% one-star. We could not check LegitScript or the BBB. Compounded GLP-1s are not FDA-approved products.

Enhance.MD’s reviews and regulatory checks

What we found on Sep 20, 2026, and where we looked.

  • FDA: No warning letter found for “enhance.md” or “enhancemd” in the FDA warning-letter database. We did not search under its medical-group names. Source, accessed Sep 20, 2026.
  • Trustpilot: TrustScore 4.0 from 160 reviews: 68% five-star and 14% one-star. We did not analyse the one-star reviews individually. Source, accessed Sep 20, 2026.
  • BBB: Not checked: bbb.org blocks our connection.
  • LegitScript: Not checked: the legitscript.com checker had reached its weekly lookup limit.

Absence of a record is not proof of a clean record. Counts change; check each source before you decide.

Enhance.MD FAQs

Is Enhance.MD legit?
Enhance.MD names three partner pharmacies in its FAQ (Tru Meds Rx, Strive Pharmacy and Pharmacy Hub) and publishes a support phone line. We found no FDA warning letter to Enhance.MD in the FDA database on Sep 20, 2026. Its Trustpilot score is 4.0 from 160 reviews with 14% one-star. A licensed clinician makes every prescribing decision.
How much does Enhance.MD cost per month?
On Sep 20, 2026 its Core semaglutide page listed $249 per 4 weeks on the 1-month plan, $237 on the 3-month plan, $224 on the 6-month plan and $212 on the 12-month plan, which is billed every 48 weeks. Advanced tirzepatide runs $329, $313, $296 and $280 on the same plans. Its FAQ says the price includes labs, provider visits, medication and shipping.
Does Enhance.MD accept insurance?
No (HSA/FSA eligible)
Which medications does Enhance.MD prescribe?
Compounded semaglutide (GLP-1 Core); Compounded tirzepatide (Advanced); Semaglutide + tirzepatide (Elite); Microdose tirzepatide; NAD+ therapy / wafers.
Does it require labs?
Yes; metabolic labs every 6 months, included
Which states does Enhance.MD serve?
Not published. Not served: Not published.
Can I cancel Enhance.MD?
Its FAQ says you can pause or cancel at any time by email or by calling 888-299-5088, and that membership renews automatically every 28 days. Its terms say the subscription auto-renews unless cancelled before the next billing cycle and that full payment terms are shown at checkout. We found no published refund terms for prepaid 3, 6 or 12-month plans, so ask before prepaying.
Are the medications FDA-approved?
Compounded semaglutide and tirzepatide are not FDA-approved products and their availability can change if the FDA finalises its proposed 503B bulks-list exclusion.

Enhance.MD: the takeaway

Enhance.MD suits someone who wants labs included and is sure enough to prepay. Compare it on the $249 four-week price unless you will commit to a year, and ask about refunds on prepaid plans before paying.

Check if you qualify → Not sure you qualify? Take the quiz
Sources
  1. FDA: Human drug compounding — accessed Sep 1, 2026
  2. Enhance.MD home page — accessed Sep 20, 2026
  3. Enhance.MD GLP-1 Core semaglutide — accessed Sep 20, 2026
  4. Enhance.MD GLP-1 Advanced tirzepatide — accessed Sep 20, 2026
  5. Enhance.MD FAQ — accessed Sep 20, 2026
  6. Enhance.MD Terms of Service — accessed Sep 20, 2026
  7. Trustpilot: enhance.md — accessed Sep 20, 2026

DoIQualify may earn a referral fee if you enroll through links on this page. This does not affect our rating. We are not a healthcare provider; eligibility and prescribing decisions are made by each program's licensed clinicians. Prices verified Sep 20, 2026 and may change. Compare Enhance.MD’s price with 36 other programs. How we rank · Medical disclaimer

Enhance.MD · $112/mo
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